The Transamerica Pyramid sits high atop the city of San Francisco
Financial District - San Francisco
True to its name, the Financial District is San Francisco's business center. Home to banks, oil companies, insurance agencies, advertising agencies and still plenty of technology firms. The difference between San Francisco Financial District and New York City is that people actually wait for the lights to change. The Financial District was originally the "Barbary Coast" which is normally known for the center of gambling, prostitution and a wild night life.
Bordered by Washington, Market and Montgomery Streets
A The Transamerica Pyramid (pictured) is easily the the city's most recognizable structure at 48 stories tall. Unfortunately, there is no roof top or public access allowed. It's a just a beautiful building to look at, especially from the Ferry to Sausalito during your San Franicsco tour aboard San Francisco Comprehensive Shuttle Tours.
In the Bank of America Center, look out for the Carnelian Room at the top floor as it has some of the best views the city has to offer.
Also, if you have time, check out or walk through Jackson Square Historical District. It's a compact neighborhood within a neighborhood that is now a mixed array of shops and nice-looking offices.